Orenitram is a drug used to treat pulmonary arterial hypertension (PAH), high blood pressure specifically in the arteries of the lungs. Orenitram belongs to a class of drugs known as vasodilators. It works by widening the arteries and decreasing the amount of blood clotting platelets in the lungs and other parts of the body so that blood can flow more easily.
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Orenitram is usually used to treat pulmonary arterial hypertension. Orenitram may also be used to improve the ability to exercise. It is however advisable to take the drug regularly to get the most benefit from it. For further guidelines on how to use Orenitram, it is recommended to seek the doctor"s advice. People who are allergic to treprostinil and severe liver disease are also advised not to use the drug as it may cause lead to many complications. Those who are pregnant or may become pregnant should also consult the doctor before taking Orenitram to prevent any harm to the unborn baby. Below you will find the uses of Orenitram.
- Pulmonary arterial hypertension
Dosage of Orenitram depends on the individual and the condition being treated. You should take medication precisely as your doctor prescribes it. Orenitram tablets should be taken with food and swallowed as a whole. Crushing, splitting or chewing the Orenitram tablet is not recommended. It is important to seek the doctor"s advice if you miss a dose. Below you will find a typical dosage of Orenitram.
- The starting dose of Orenitram is 0.25 mg twice daily, taken approximately 12 hours apart or 0.125 mg three times daily, taken approximately 8 hours apart
- The dose should be increased only as tolerated to achieve optimal clinical response. The preferable increment is 0.25 or 0.5 mg or 0.125 mg every 3-4 days
- If the dose increments are not well-tolerated, one should consider titrating it slower
Orenitram Side Effects
Treprostinil, the active ingredient contained in Orenitram, may cause unwanted side effects that require medical attention. Mild or subsiding side effects do not require medical attention and may stop as your body becomes accustomed to the medication. The following are some of the common side effects associated with the use of Orenitram. Note that not all possible side effects are listed.
- Decreased urine
- Dry mouth
- Increased thirst
- Irregular heartbeat
- Muscle pain or cramps
- Unusual tiredness or weakness
- Redness of the face, neck, arms, or upper chest
Like any drug, Orenitram may interact with other drugs and substances. Interactions can cause Orenitram to change the way it is supposed to function in the body. Interactions can also cause serious side effects for the patients. Patients should make a list of all the medication they are using to assist the doctor during prescription. Below you will find a list of drugs that may interact with Orenitram. Note that not all possible interactions are listed.