Metoprolol is a cardioselective beta1-adrenergic receptor blocker that is used for the preventative treatment of angina. It has shown effectiveness in reducing mortality in patients after MI and in treating angina. It is available in oral (immediate-release and long-acting) and parenteral (injectable) forms. Intravenous metoprolol is commonly administered in hospitalized patients after an MI and is used in treatment for hypertension in patients unable to take oral medication.
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Metoprolol can help treat symptoms of angina, heart failure, and hypertension due to inadequate blood flow to the heart. The drug works by impacting the nerve impulses in the heart and other areas. Taking Metoprolol can also help patients avoid further damage to blood vessels, heart attacks, stroke, and kidney failure. This medication may also be used to prevent further cardiac problems after myocardial infarction and may be used to prevent headaches in those patients suffering from migraines.
Below you will find the different types of conditions that can be treated by using Metoprolol:
- Heart Failure
Metoprol comes as a tablet and an extended, release tablet that are to be taken orally with 8 oz. of water. The tablet formulation is taken once or twice daily with meals or shortly after whereas the extended, release tablet is taken once a day.
Usual dose for Hypertension
- Adult dosage for hypertension starts with 100 mg, in one or 2 divided doses, maintained at a strength of 100 to 450 mg a day.
- Adult dosage for supraventricular tachycardia starts with 100 mg by mouth in 1 or 2 divided doses, maintained at a strength of 100, 450 mg a day.
Usual dose for Myocardial Infarction:
- Early treatment - 3 bolus injections of 5 mg given every two minutes. Patients who tolerate the full IV dose should begin Metoprol 50 mg tablets every 6 hours and should begin 15 minutes after the last IV dose, continuing for 48 hours then maintained at a strength of 100 mg twice a day.
- Late treatment, Take 100 mg by mouth two times a day.
Metoprolol Side Effects
The side effects of beta 1 blockers result in their ability to block beta-adrenergic receptors in various areas of the body. Resulting in chronotropic and inotropic effects. Below is a list of side effects of Metoprolol. Note, this list does not include all side effects that may occur.
Like many other drugs, Metoprolol may interact with other drugs. The more common drug interactions are listed below. Be advised that this list does not include every possible drug interactions.
- Calcium channel blockers (diltiazem, verapamil)
- Insulin and oral antidiabetic drugs