Alzheimer’s Disease Linked To Overactive Immune System

In a new study, scientists found links between Alzheimer’s disease to an overactive immune system. According to the findings, a chemical that is known to reduce neuroinflammation was used to stop changes related to memory and behavior- which is characterized as Alzheimer’s disease.

“With an aging population and no new dementia drugs in over a decade, the need to find treatments that can slow or stop disease progression is greater than ever.”- With excitement from the findings, Dr. Doug Brown, Director of Alzheimer’s Society, in an interview with BBC.

According to statistics, about 10% of Seniors over the age of 65, and 50% of over 85 years and above are affected with Alzheimer’s disease. This disease affects about 5.3 million Americans, and it is predicted to reach 5.5 million people in the next few years. By 2050 14 million Americans will be affected with Alzheimer’s disease.

Inflammation of the neurons in the brain which is as a result of immune system is now highly suspected to be the major cause of Alzheimer’s disease. The brain contains immune cells known as microglia. The function of the microglia cells is to release inflammatory immune factors: interleukin-1 and interleukin-6. In reference to experimental studies and clinical trials carried out in animals and humans, these inflammatory immune factors were seen to destroy neurons in the brain of those with the Alzheimer’s disease. Destruction of neurons was stopped when the interleukin-1 and interleukin -6 were blocked in some animals.

According to Gomez-Nicola, lead author of a research published in the Journal Brain, “These findings are as close to evidence as we can get to show that this particular pathway is active in the development of Alzheimer’s disease.”

Anti-inflammatory nutrients were also suggested in the study. These nutrients have the ability to stop the secretion of interleukin-1 and interleukin-6. A study conducted at the University of California showed that both low and high doses of curry spice curcumin can help limit the inflammatory effects of immune factors.

According to a report printed in the Journal of the American Medical Association,  vitamin  C, vitamin E, beta-carotene with some other minerals may help protect individuals against Alzheimer’s disease. They are powerful anti-inflammatory nutrients that stop the activities of interleukin-1 and interleukin-6.They protect our brains against assault.

Although no extensive studies have been conducted on these nutrients for their direct prevention of Alzheimer’s disease they are considered excellent when it comes to the prevention of Alzheimer’s disease. Though too early to make recommendations, making these nutrients part of your daily diet could help you prevent Alzheimer’s disease.